A Facile Synthesis and Docking Studies of N-(3-(4-Chlorophenoxy)benzyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Abstract

A simple method was developed to synthesize <em>N</em>-(3-(4-Chlorophenoxy)benzyl)-2-methyl-7<em>H</em>-pyrrolo[2,3-d]pyrimidin-4-amine by coupling 3-(4-Chlorophenoxy)phenyl)methanamine and 4-chloro-2-methyl-7<em>H</em>-pyrrolo[2,3-d]pyrimidine. The products have been obtained in good yields and were characterized by spectral analyses and finally, docking studies were carried out.