Interaction of Thallium (I) with Cytidine 5 -Monophosphate in Different Ionic Strengths and Various Media

Abstract

The formation constants of the species formed in the systems H+ + cytidine 5 -monophosphate (CMP)<br />and H+ + cytidine 5 -monophosphate + Tl (I) ion have been determined in aqueous solution in a wide<br />pH range of 1.5 to 10.5 at 25 °C and different ionic strengths ranging from 0.1 to 1.5 moldm-3<br />NaClO4, NaNO3, and NaCl using potentiometric-spectrophotometric technique. The composition of<br />the complexes was specified and was shown that thallium ion forms mononuclear two 1:1 complexes<br />with CMP. The general trend for the protonation constants of CMP and its complexes with thallium<br />(I) are in the order of NaClO4> NaNO3> NaCl in different ionic media. The dependence of formation<br />constants on ionic strength are described by a Debye-Huckel type equation and interpreted for the<br />various supporting electrolytes.