The Effect of Vitamin C and E Supplementation on CRP, IL- 6, Lymphocyte,Cortisol and Lactate Response Following one Aerobic Training Session

Abstract

Introduction: The aim of this research was to compare the effect of a 15-day vitamin C and E<br />supplementation on C reactive protein (CRP), interleukin- 6 (IL-6), cortisol, lymphocyte, and<br />lactate response to a single aerobic training session. Methods: Thirty male college students of<br />Islamic Azad University-Fars Science and Research Branch of with mean age of 21/53±2/99<br />years, weight 70/03±10/52 kg and height 176±5/97 cm voluntarily contributed in this research.<br />First aerobic power of all subjects was estimated and the data was used to divide the subjects<br />into three 10-persons groups (vitamin C group, vitamin E group and placebo group). A matched<br />study design was used; hence, all target variables were measured before and after the treatment<br />after the subject ran for 30 minutes on treadmill intensity of 75. The data was analyzed using<br />ANOVA, ANOVA repeated measure and dependent t test with bonferroni adjustment (p ≤ 0.05).<br />Findings: Results showed that the 15-days vitamin C and E supplementation had no significant<br />effect on the level of CRP, IL-6, cortisol, lymphocyte, and lactate at rest, after exercise and one<br />hour after exercise. Conclusion: Further research is required to explore the impact of vitamin<br />C/E administration on the level of CRP, IL-6, cortisol, lymphocyte, and lactate in different<br />exercise conditions, using higer doses of these substances.