SCREENING FOR ANTIBIOTIC RESISTANT BACTERIA IN URINE SAMPLES

Abstract

Chronic urinary tract infections are often caused by antibiotic resistant bacteria. In some of these cases, prediction of the most effective antibiotic (s) may urgently be needed. This can not be achieved unless the nature and patterns of the resistance to antibiotics among the pathogenic bacteria has been described earlier. The urine samples that reached the laboratory of Shaheed Mustafa Khomeini Hospital (SMKH) during a two-year period were screened for the incidence, nature, percentage and patterns of antibiotic resistant bacteria. Theresultsshowed that about 92% of the total isolates were related to the Enterobacteriacae group and more than 94% of these strains were resistant to two or more antibiotics simultaneously. Nalidixic Acid, Amikacin, and Nitrofurantoin were classified as the most effective antibiotics. While Ampicillin, Cephalothin and Carbencillin were found to resist more than75% of the totalisolatedpathogens. The percentages of resistance to other antibiotics ranged between 41% and72% These results suggest that more restrictions should be imposed on the sale and/or use of antibiotics in Iran.