Volume 15, Issue 3
مرور بر اساس
ارسال های اخیر
-
The effects of an Aloe-based polyherbal formulation on fertility parameters in male rats
(Mashhad University of Medical Sciences, 2025-05-01)Objective: Aloe dry juice as a purgative agent is widely used in phytotherapy. In Iranian traditional medicine to decrease Aloe side effects, some plants are added, and this polyherbal formulation is named "Ayarij-e-Faiqra" ...
-
Signaling pathway in breast cancer therapy
(Mashhad University of Medical Sciences, 2025-05-01)Objective: This research attempted to increase the bioactivity and solubility and reduce the side effects of Tamoxifen (TMX) by using the cellulose nanocrystals (CNCs) extracted from walnut shells as a carrier and studied ...
-
Antidiabetic effects of Peganum harmala seed extract on streptozotocin-induced diabetes in rats
(Mashhad University of Medical Sciences, 2025-05-01)Objective: Diabetes, a chronic metabolic disease, has many complex complications and an increasing prevalence in various societies. Despite conventional drug treatments and limited surgical and tissue transplant methods, ...
-
The hydroalcoholic extract of Nasturtium officinale protectively inhibits apoptotic and inflammatory pathways in hepato- and nephrotoxicity: An in vivo study
(Mashhad University of Medical Sciences, 2025-05-01)Objective: Nasturtium officinale (N. officinale (NO)) has been widely used in traditional medicine. This study investigates the protective effects of NO against hepatic and renal damage induced by CCl4 and gentamicin, ...
-
Protective effect of menthol against diethylnitrosamine-induced hepatocellular carcinoma in mice by downregulating CTNNB1 and HIF-1α
(Mashhad University of Medical Sciences, 2025-05-01)Objective: This study examined the impact of menthol, a natural monoterpene, on diethylnitrosamine (DEN)-induced molecular and histopathological changes in the livers of male mice.Materials and Methods: Forty male mice ...
-
Effects of sumac aqueous extract along with eating and drinking modification on functional dyspepsia symptoms in comparison with omeprazole: An open-label, randomized, controlled clinical trial
(Mashhad University of Medical Sciences, 2025-05-01)Objective: Functional dyspepsia (FD), a common gastrointestinal problem. The aim of the study was to evaluate the influence of Rhus coriaria L. (sumac) on FD.Materials and Methods: This randomized controlled clinical trial ...
-
The effects of saffron supplementation on inflammatory factors and clinical outcomes in sepsis patients admitted to the intensive care unit (ICU): Study protocol for a double-blind randomized controlled clinical trial
(Mashhad University of Medical Sciences, 2025-05-01)Objective: Research studies have examined saffron's effects on inflammation, infection, and oxidative stress. Nevertheless, the effects of saffron on sepsis patients in the intensive care units (ICUs) have not yet been ...
-
Investigating the potential effects of olive leaves and ginger rhizome extracts on kidney and liver functions in alloxan-induced diabetic rats
(Mashhad University of Medical Sciences, 2025-05-01)Objective: Although there are many drugs on the shelves of pharmacies to manage diabetes mellitus (DM), many people around the world still use herbal preparations to treat it. This study investigated the effect of an aqueous ...
-
The role of Anvillea garcinii and its compounds in health and disease: An overview
(Mashhad University of Medical Sciences, 2025-05-01)Objective: This scoping review aims to examine the potential health benefits of Anvillea garcinii and its compounds and provide recommendations based on available research. A. garcinii is a plant species in the daisy family ...
-
Atorvastatin and flaxseed dietary treatments improve dyslipidemia and liver injuries in a diet-induced rat model of non-alcoholic fatty liver disease
(Mashhad University of Medical Sciences, 2025-05-01)Objective: Non-alcoholic fatty liver disease (NAFLD) as the most common chronic liver disease is associated with metabolic disorders including dysregulated lipid and glucose metabolism. There is no approved drug treatment ...
-
Preventive and therapeutic effects of Nasturtium officinale hydroalcoholic extract on cyclophosphamide-induced testicular toxicity in rats
(Mashhad University of Medical Sciences, 2025-05-01)Objective: Cyclophosphamide (Cy) as an alkylating chemotherapeutic agent with broad-spectrum efficacy in cancer treatment. Despite its wide spectrum of clinical usage, off-target multiple organ toxicity such as sperm and ...
-
Neuroprotective effects of hesperidin and auraptene on 6-hydroxydopamine-induced neurodegeneration in SH-SY5Y cells
(Mashhad University of Medical Sciences, 2025-05-01)Objective: Destruction of dopaminergic neurons causes diseases. Various compounds with neuroprotective and antioxidant properties have been identified, including Hesperidin (HES) and Auraptene (AUR). We aimed in this study ...



