مرور Volume 2, Issue 2 بر اساس موضوع "AutoDock"

در حال نمایش موارد 1 - 1 از 1

In silico evaluation of rare codons and their positions in the structure of cytosine deaminase and substrate docking studies

Mortazavi, Mojtaba؛ Nezafat, Navid؛ Negahdaripour, Manica؛ Gholami, Ahmad؛ Torkzadeh-Mahani, Masoud؛ Lotfi, Safa؛ Ghasemi, Younes (Shiraz University of Medical Sciences, 2016-06-01)

Cytosine deaminase (CDase) is used with 5-fluorocytosine (5FC) for genetic cancer treatment. This approach has several undesirable features, such as a relatively poor turnover of 5FC and low prodrug conversion activities, ...