نمایش مختصر رکورد

dc.contributor.authorOladejo, Opeyemien_US
dc.contributor.authorOseni, Saiduen_US
dc.contributor.authorKyallo,, Martinaen_US
dc.contributor.authorEntfellner, Jean-Bakaen_US
dc.contributor.authorTor, Noahen_US
dc.contributor.authorTiambo, Christianen_US
dc.contributor.authorPelle, Rogeren_US
dc.date.accessioned1402-08-19T18:10:28Zfa_IR
dc.date.accessioned2023-11-10T18:10:29Z
dc.date.available1402-08-19T18:10:28Zfa_IR
dc.date.available2023-11-10T18:10:29Z
dc.date.issued2023-09-01en_US
dc.date.issued1402-06-10fa_IR
dc.date.submitted2022-08-22en_US
dc.date.submitted1401-05-31fa_IR
dc.identifier.citationOladejo, Opeyemi, Oseni, Saidu, Kyallo,, Martina, Entfellner, Jean-Baka, Tor, Noah, Tiambo, Christian, Pelle, Roger. (2023). Evaluation of Genetic Variability in Four Nigerian Locally-Adapted Chicken Populations Using Major Histocompatibility Complex-Linked LEI0258 Microsatellite Marker. Poultry Science Journal, 11(2), 189-201. doi: 10.22069/psj.2023.20536.1854en_US
dc.identifier.issn2345-6604
dc.identifier.issn2345-6566
dc.identifier.urihttps://dx.doi.org/10.22069/psj.2023.20536.1854
dc.identifier.urihttps://psj.gau.ac.ir/article_6565.html
dc.identifier.urihttps://iranjournals.nlai.ir/handle/123456789/1039363
dc.description.abstractMajor Histocompatibility Complex (MHC) is a group of genes that generally influence immune response in vertebrates, and it has been explored among different animal species in various countries. However, there is a paucity of information on its application in Nigerian locally-adapted chickens (NLAC). This research investigated genetic polymorphism, allele variability, and genetic relationships using LEI0258 major histocompatibility complex-linked microsatellite marker among four NLAC populations: Fulani × Yoruba ecotypes, FUNNAB Alpha × Noiler breeds. Blood samples were randomly collected from 50 mature birds in each population and DNA was extracted and subsequently subjected to PCR, Sanger sequencing, and bioinformatic analysis. There were two variable numbers of tandem repeats (VNTRs), with 90% of the alleles containing only one R13 and varying numbers of the R12 motifs that ranged from 1 to 19. Additional polymorphism was revealed by the presence of five SNPs and three indels in the upstream and downstream regions of LEI0258. A total of 48 alleles were observed with sizes ranging from 188 to 530 base pairs while the allele frequencies within the populations ranged from 1.9 to 29.2%. However, only 17 out of the 48 alleles had corresponding MHC-B haplotypes. Haplotypes B2, B12, and B21 found in this study had been reported to confer resistance to infectious poultry diseases especially avian influenza in locally adapted chickens. There were high allelic variability and genetic polymorphisms observed via the atypical LEI0258 microsatellite in describing the MHC-B region.en_US
dc.format.extent1163
dc.format.mimetypeapplication/pdf
dc.languageEnglish
dc.language.isoen_US
dc.publisherGorgan University Of Agricultural Sciences & Natural Resourcesen_US
dc.relation.ispartofPoultry Science Journalen_US
dc.relation.isversionofhttps://dx.doi.org/10.22069/psj.2023.20536.1854
dc.subjectCharacterizationen_US
dc.subjectgenetic diversityen_US
dc.subjectImmune responseen_US
dc.subjectLEI0258 markeren_US
dc.subjectNigerian locally-adapted chickenen_US
dc.titleEvaluation of Genetic Variability in Four Nigerian Locally-Adapted Chicken Populations Using Major Histocompatibility Complex-Linked LEI0258 Microsatellite Markeren_US
dc.typeTexten_US
dc.typeOriginal Paperen_US
dc.contributor.departmentAnimal Science and Fisheries Management, College of Agriculture, Engineering and Science, Bowen University, Iwo, Osun State, Nigeriaen_US
dc.contributor.departmentDepartment of Animal Sciences, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeriaen_US
dc.contributor.departmentBiosciences eastern and central Africa-International Livestock Research Institute (BecA-ILRI) Hub, Nairobi, Kenyaen_US
dc.contributor.departmentBiosciences eastern and central Africa-International Livestock Research Institute (BecA-ILRI) Hub, Nairobi, Kenyaen_US
dc.contributor.departmentDepartment of Animal Breeding and Physiology, Federal University of Agriculture, Makurdi, Benue State, Nigeriaen_US
dc.contributor.departmentBiosciences eastern and central Africa-International Livestock Research Institute (BecA-ILRI) Hub, Nairobi, Kenyaen_US
dc.contributor.departmentCentre for Tropical Livestock Genetics and Health (CTLGH) – ILRI, Nairobi Kenyaen_US
dc.citation.volume11
dc.citation.issue2
dc.citation.spage189
dc.citation.epage201
nlai.contributor.orcid0000-0003-3165-1677
nlai.contributor.orcid0000-0002-3060-4302
nlai.contributor.orcid0000-0003-2837-5325
nlai.contributor.orcid0000-0002-8282-1325
nlai.contributor.orcid0000-0001-8865-3775


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