| dc.contributor.author | norouzi, neda | en_US |
| dc.contributor.author | Bonyadi, Mortaza | en_US |
| dc.contributor.author | Babaei, Esmaeil | en_US |
| dc.contributor.author | Jabbarpour Bonyadi, Mohammad Hossein | en_US |
| dc.contributor.author | Javadzadeh, AliReza | en_US |
| dc.date.accessioned | 1399-08-21T22:31:10Z | fa_IR |
| dc.date.accessioned | 2020-11-11T22:31:11Z | |
| dc.date.available | 1399-08-21T22:31:10Z | fa_IR |
| dc.date.available | 2020-11-11T22:31:11Z | |
| dc.date.issued | 2017-07-01 | en_US |
| dc.date.issued | 1396-04-10 | fa_IR |
| dc.identifier.citation | (1396). مجله مطالعات علوم پزشکی, 28(4), 16-21. doi: 10.18869/acadpub.umj.28.4.16 | fa_IR |
| dc.identifier.issn | 2717-008X | |
| dc.identifier.uri | https://dx.doi.org/10.18869/acadpub.umj.28.4.16 | |
| dc.identifier.uri | http://umj.umsu.ac.ir/article-1-3457-en.html | |
| dc.identifier.uri | https://iranjournals.nlai.ir/handle/123456789/487188 | |
| dc.description.abstract | Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD).
Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and control groups were originated from Northwest of Iran. Genotypes of both groups were determined by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP).
Results: Investigation of the association of p.Gly119Arg polymorphism in CFI gene with AMD showed that there are no statistically significant differences between patients and controls in genotype and allele frequencies of this polymorphism (P˃0/05).
Conclusion: Our result show that p.Gly119Arg polymorphism of the CFI gene is unrelated to the susceptibility to AMD in Northwest of Iran. | en_US |
| dc.format.extent | 241 | |
| dc.format.mimetype | application/pdf | |
| dc.language | English | |
| dc.language.iso | en_US | |
| dc.publisher | دانشگاه علوم پزشکی ارومیه | fa_IR |
| dc.relation.ispartof | مجله مطالعات علوم پزشکی | fa_IR |
| dc.relation.ispartof | Studies in Medical Sciences | en_US |
| dc.relation.isversionof | https://dx.doi.org/10.18869/acadpub.umj.28.4.16 | |
| dc.subject | AMD | en_US |
| dc.subject | polymorphism | en_US |
| dc.subject | CFI gene | en_US |
| dc.subject | ژنتیک | en_US |
| dc.title | Association of CFI gene polymorphism with age related macular degeneration in Northwest of Iran | en_US |
| dc.type | Text | en_US |
| dc.type | Research | en_US |
| dc.contributor.department | Tabriz University | en_US |
| dc.contributor.department | Tabriz of University | en_US |
| dc.contributor.department | Tabriz of University | en_US |
| dc.contributor.department | Ophthalmic Research Center Shaheed Beheshti University of Medical Sciences & Health Services, Tehran, Iran | en_US |
| dc.contributor.department | Tabriz University of Medical Scinces | en_US |
| dc.citation.volume | 28 | |
| dc.citation.issue | 4 | |
| dc.citation.spage | 16 | |
| dc.citation.epage | 21 | |
