Comparising the Succinylcholine onset effect with Atracurium - Alfentanyl in patient underwent rapid sequence Induction

Abstract

Background: Succinylcholine is the most anesthetic drug used to muscle relaxation in emergency endotracheal intubation. Unfortunately it can have serious side effects. The perpose of our study was to comparison of Atracurium + Alfentanyl with succycholine. Materials and Methods: In this clinical trial study, one hundred patient randomly designated two group succinylcholine (control group) & Atracurium + Alfentanyl (experimental) after injecting of thiopental as a Alternative Method for R.S.I we can assess the difference between this two groups, with regarding to condition of intubations such as jaw relaxation, vocal cord movement and bucking. Findings: Results showed that 38% of patient had mild bucking in Atr + Alf group but all patients in succylin group were not seen (p<0.0001). Vocal cord movements was seen in expelinental group but there wasn’t in control group. Conclusion: According to results, use of Atra + Alfen method can replace the standard method (succinylcholine) for contraindicated condition. Mild vocal cord movement and mild bucking in the Atracurium + Alfentanyl can be control by that a increase in Atracurium dose.