Evaluation of antibiotic resistance in patients with urinary tract infection , khorramabad Madani hospital 2001-2002

Abstract

Introduction: Urinary tract infection is a common bacterial infection in childhood . Approximately 3-5% of girls and 1% of boys acquire a urinary tract infection (UTI). The management of UTI is complicated by the increasing prevalence of antibiotic- resistant strains and over the - counter antibiotics empiric therapy with antibiotics such as ampicillin , amoxicillin and cotrimoxazole world cost more and lead to widespread antibiotic resistance . Materials and Methods: In this study we aimed at assessment of prevalence of antibiotic resistance in 127 patients with positive urine culture based on antibiogram results. This cross- sectional study was performed in Khorramabad Madani hospital during 2001-2002. 62/2% of the patients were female and 37.8% were male. Findings: Culture results were : Ecoli (73.3%), proteus (12.6%) , klebsiela(9/4%), Entrobacter(3.1%) , Citerobacter (0.8%), Yersinia (0.8%). Overall antibiotic resistance was 96.9% and resistance to antibiotics, were: Ampicillin(88.2%), Amoxicillin (86.6%), Cotrimoxazole (75.6%), Nitrofurantoin (18.9%), Nalidixic acid (10.2%), Cefixim (4.7%) , Ceftriaxon (3.1%) Gentamicin (11.8%), Amikacin (3.1%). Conclusion: Results showed that antibiotic resistance for over- the counter antibiotics was significant .